Side Effects of DIM. Why DIM Alone Isn't Enough For Estrogen Dominance Get plenty of lubricants like K-Y Jelly or any other lube you use to have sex. If you have been following me, you might have seen the pre- and post-surgery protocol I created when facing a double hip replacement (on August 28, 2017). It helps keep my period-induced cystic acne at bay, reduces PMS symptoms and helps me be a generally happier person. Drugs for Treatment and Risk Reduction: Tamoxifen. However, menstrual cycles tend to shorten and become more regular as you age. A plant based whole unprocessed food diet is recommended to help shrink fibroids. That was when I added DIM to my regimen and that was when everything went haywire. Read more about me here. She suggested Aygestin (synthetic progesterone) to get it back in phase or an ablation. The Best Supplements for Healthy Digestion, How to Get the Protective Power of Vitamin K, Helps prevent the effects of estrogen on cells, Lowers toxins produced by your bodys natural metabolism. I know the dosage is low compared to what is advised on this site. How do I stop side leaks during my period? - coalitionbrewing.com There is no preference on which method you use, instead, try to find what works best for your schedule and stick to it. Try some relaxation methods. It's difficult not to pay attention to every little twinge in your body during the TWW and wonder, "Could this be a sign of early pregnancy?" Men trying to manage their testosterone levels may turn to estrogen blockers to help balance their hormones. Read Guide to using progesterone for women's health. Although this web site is not intended to be prescriptive, it is intended, and hoped, that it will induce in you a sufficient level of scepticism about some health care practices to impel you to seek out medical advice thatis not captive to purely commercial interests, or blinded by academic and institutional hubris. You can wear gloves if you prefer. DIM is supposed to help regulate estrogen levels in the body, while research on it is relatively restricted ( 1 ). The advised dosage of 100 to 200 mg of DIM per day for women and 200 to 400 mg of DIM per day for men in the book All About DIM refers to milligrams of such an absorbable formulation. DHT is the form of testosterone associated with prostate cancer in men and conditions like hirsutism (hair where you dont want it) and acne in women. Keep in mind that 16OHE1 is the type that can lead to mastalgia and may stimulate estrogen-sensitive cancer cells, like breast cancer. Periods that are irregular. Glucuronidation is one of the major detoxification pathways of the liver. From erratic (and often, heavy) periods to weight gain, as well as hot flashes, swollen breasts and mood swingsthese symptoms are quite common during perimenopause. Luine VN. September 1, 2019 at 8:39 am. Those given DIM experienced significant improvements in prostate health, as well as PIN (14). Notably, a mouse study found that DIM helped prevent cervical cancer. A fierce patient advocate and completely dedicated to uncovering the root cause of hormonal imbalances, Dr. Brighten empowers women worldwide to take control of their health and their hormones. They are responsible for producing estrogen and regulating the menstrual cycle. There is also data to support its benefits in certain cancers. Limited studies suggest that DIM supplements may help reduce prostate enlargement and protect against certain cancers. I was eating right and exercising, but everything felt tight. Diindolylmethane. DIM supplements are neither poisonous or have major negative effects, according to current human studies. I have been using progesterone cream for the last two luteal phase cycles (very irregular 50ml doses a day/every second or third days). When the endometrial lining is overstimulated it can result in endometrial hyperplasia, which can lead to heavier periods. All medications and supplements have a risk of interacting with one another, and DIM is no different. Levels of a certain kind of estrogen may lead to higher risks of cancer in men, just as it can in women. Physical activity: Getting regular physical activity has been proven to relieve PMS symptoms like bloating. Ugh!! Dim lighting has been known to help regulate the release of hormones that cause your period to arrive. I didn't want to do either. This can help prevent headaches and other unwanted issues that can arise when using a Phase 1 nutrient alone. Estrogen imbalance or excess estrogen, often called estrogen dominance can lead to a cascade of undesirable symptoms like hormonal headaches, breast tenderness, and PMS, to name a few. Learn more about Balance Womens Hormone Support. In people with diabetes, this insulin response is not adequate. For instance, some studies suggest DIM encourages the death of cancer cells. While we understand the mechanism by which this may work and many women report benefits, it is important to note that research is lacking. Let us know in the comments. Also, it is asked, How quickly does DIM work? If you are struggling with heavy periods, tender breasts, mood swings, hot flashes and water retention, there is a high chance that you are estrogen dominant. However, in a 6-month study in 551 women with cervical abnormalities, taking 150 mg of DIM per day had no effect on cervical cell changes (3, 13). I had some tests done at the gyn and she told me I had fibroids, possible adenomysis and that my lining was out of phase (she didn't clearly explain what that meant. Your doctor will ask about your menstrual cycle because changes in your hormone levels could indicate problems other than low-income status. Specifically, DIM may stimulate the production of a less potent, more beneficial form of estrogen known as 2-hydroxyestrone (1). Aim to exercise most days of the month. However, DIM supplements are available over-the-counter and online. ago The ovaries are a vital part of our body that play a role in women's reproductive capabilities. Cruciferous vegetables are low-calorie, and rich in folate, vitamins C, E, and K, and fiber. The only hormone metabolites known to help with appropriate levels of the free form of testosterone are the 2-hydroxy metabolites of estrogen induced by DIM. Periods will start to become irregular, until they disappear altogether. DIM alters estrogen metabolism in a beneficial way, producing more good estrogens and fewer harmful estrogens. No matter DIMs effectiveness, its always good to eat more cruciferous veggies. What is Menstruation? | Get Facts About Having Your Period Uses and potential benefits of DIM supplements, Cruciferous Vegetables: Health Benefits and Recipes. You should not rely on this information as a substitute for, nor does it replace, professional medical advice, diagnosis, or treatment, Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or homeopathic supplement, or using any treatment for a health problem. WebMD does not provide medical advice, diagnosis or treatment. In the study, a small sample of patients with thyroid proliferative disease (which includes cancer, goiter and adenoma) were given 300 mg of DIM daily for two weeks. Cruciferous vegetables contain Indole-3-Carbinol (I3C), which is converted to DIM by the body. With type 1 diabetes, the body does not produce any insulin. I'm praying that my june period is better. The most common side effect was darkening of the urine. Most of the time, rest and over-the-counter medications help. Changing your diet and exercising regularly can help you achieve your weight loss goals and restore regular menstruation. I am not due for my yearly and another PAP until November. It takes a lot of DIM to mess with your sodium on its own, but if youre taking diuretics, you might reach your limit faster. Shrink Fibroids the Truth about Estrogen Dominance in Stressful Times If youve been struggling with PMS symptoms, heavy periods, acne, breast tenderness or symptoms of PCOS or perimenopause then youve probably come across a DIM supplement as a solution. When you eat cruciferous vegetables, your stomach acid breaks down a compound called indole-3-carbinol to produce a new compound called DIM (3). The majority of individuals find that taking DIM first thing in the morning with a glass of water and a little amount of food is the best way to proceed. Aromatase is an enzyme that assists in the conversion of testosterone to estrogen. However, a study in 24 healthy people found that although DIM doses of up to 200 mg were well tolerated and didnt cause side effects, one person experienced nausea, headache, and vomiting after taking a 300-mg dose, suggesting that higher doses may be associated with adverse side effects (15). 10 Supplements You Should Be Taking After Menopause Estradiol and cognitive function: past, present and future. Hypothyroidism, or an underactive thyroid, can cause your period to be irregular, with heavier and less frequent periods. Its important to note that a higher dose of DIM was used because this was a study on patients with thyroid proliferative disease. I'm just wondering if it works for some and not others. DIM supplements are purported to aid other hormone-related conditions. Even if you eat plenty of veggies, you may not get much DIM if cruciferous vegetables arent a regular part of your meals. Diindolylmethane | Memorial Sloan Kettering Cancer Center As for the second question, the answer is yes, you can try diming out for yourself. This is why you must take the dosage of the supplement into account. Questions about DIM. My May period came on day 23 (not great but more the norm for me) and my breasts were not as sore. Estrogen increases fluid retention, but progesterone decreases that additional fluid by acting as a diuretic. I'm wondering now if the brand I was using was possibly the problem. Continuous-dosing pack. Taking DIM in high amounts can cause adverse side effects such as vomiting, headaches and nausea. I'm especially excited to hear that it has helped thicken your hair. Hi Shari Most people are lead to believe DIM reduces oestrogen levels, it doesn't. It changes the ratio of bad oestrone to better. The night sweats come about 11 days before my period and can run into when I have my period. Youll also benefit from the other vitamins, minerals, and fiber they provide. I don't feel like the lugol's is doing much for me. How? When exposed to stomach acid, these enzymes form a compound called indole-3 carbinol. See what's being discussed, ask for help, give your thoughts or experiences, or just browse Its free and will bring you important new information on progesterone therapy and related health matters, Home|Contact|Newsletter|Index of Symptoms|News|Progesterone cream|Privacy policy|Blog|About|FAQ. Research shows that about one in three cancer deaths is related to poor nutrition and could be prevented. All the same, human studies are needed (10, 11, 12). While DIM is often used to support hormone balance in premenopausal women, it also may cause hormonal disturbances. Dr. Brighten is an international speaker, clinical educator, medical advisor within the tech community, and considered a leading authority on womens health. Perimenopause occurs between the ages of 40 and 50. Bones that are weak or fragile. Thanks so much Diane, for your support and input in helping me figure this out. So DIM may not have much benefit. Try diuretics. If you have regular periods, take five days off from the first day of your period (day 1 to 5). While estrogen levels decrease during menopause, the truth is, estrogen levels do not fall significantly until after a woman's last period. DIM supplements should not be taken by children or women who are pregnant or breastfeeding. Sex Drive has decreased. DIM is a compound your body makes from cruciferous vegetables. The best answer I can give you is when your cycle begins, so if you dont know when your cycle has begun, then its best to ask your doctor. The Benefits of DIM - Fort Wayne Physical Medicine Towards the end of jan. 2015 I began Natpro and upped it to around 80mg. According to Traditional Chinese Medicine (TCM), coldness in the uterus is a common cause of scanty period, no . People who take dim out of concern for its potential negative effects are likely overthinking things. Current human research doesnt show DIM supplements to be toxic or have serious side effects. Your doctor can decide whether you need to switch to a different drug while taking DIM. 5 Ways to Benefit Your Fertility by Taking DIM Bleeding generally occurs only four times a year during the seven days you take the inactive pills. Fertility Herbs and Supplements Q&A Progesterone also stabilizes the HPA (adrenal) axis and supports thyroid function. I really appreciate it! Researchers concluded that, in women taking tamoxifen, DIM promoted healthier estrogen metabolite production. What Happens to Your Body During the TWW? Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Studies have shown that women in perimenopause and menopause experience a reduced health-related quality of life, as well as higher work impairment. Some women who suffer from insomnia due to estrogen dominance, perimenopause, or menopause find that taking DIM at night helps them sleep better and longer. If you do decide to take Vitex, don't take it for longer than 3-6 months maximum at a time, then stop and see how your hormones are without it. Supplements can help. When your body no longer needs estrogen it is the livers job to package it up so it can be sent out via the urine and stool. Do You Have Estrogen Dominance? Take This Assessment To Find Out When using DIM supplements, some persons have reported mild changes in urine color. Hi Im a 21 year old male, I started taking progesterone in September of this year as a supplement to my trt regime (cancer survivor under doctor supervision). Hello pls pass on this message to as many women as you can - heavy bleeding with fibroids - just take VIT B6 100 gms daily - if periods are heavy take VIT B6 either 50g mg and 50 mg Am and Pm - VIT B6 halts minimizes bleeding and prevents spotting - also load up on progesterone rich foods but VIT B6 is a simple over the counter that . If you have or suspect that you have a medical problem, contact your health care provider promptly. I shared my protocol so you don't have to do the hours of research if facing any form of surgery. After one year of DMPA injections, 50% to 75% of women report having no periods. "Both DIM and I3C [the plant nutrient isolate] induce the activity of phase I and phase II . She is the best selling author of Beyond the Pill and Healing Your Body Naturally After Childbirth. DIM -The best supplements for adult acne and hormonal acne DIM Promotes Fat Decomposition DIM is linked to estrogen metabolism, which is important for body weight regulation. DIM may specifically boost the formation of 2-hydroxyestrone, a less strong but more favorable type of estrogen ( 1 ). I stopped the DIM right after. Chasteberry and DIM are the greatest vitamins for hormone imbalance. In one study in mice on a high fat diet, 23 mg of DIM per pound (50 mg per kg) of body weight significantly reduced the formation of new fat cells (19). There are many different opinions on when to take it, but the general consensus is that taking it every day for 3 weeks will be beneficial. She is a member of the MindBodyGreen Collective and a faculty member for the American Academy of Anti Aging Medicine. Although research on DIM is still quite limited, its thought to help balance estrogen levels in your body (1). I began using about 60mg. DIM Supplement Benefits For Women - Dr. Jolene Brighten "The daily recommended intake of 600 IUs is debatable since studies show higher amounts of D are necessary for disease- and cancer-prevention benefits." Start by getting your levels checked to. Just turned 51, my dr, had me take DIM (days 1-10) and topical progesterone (days 20-27) when my period was regular, now its out of whack- haven't had it in . This indicates that it might be linked to weight reduction and good weight control. A double-blind, randomized controlled study showed that 150 Pharmaceutical researchers are taking note and testing indole carbonil-based formulations for mastalgia. At least 30 grams of fibers should be consume a day. I had stopped taking it and done more research into DIM. Linda says. Before taking these supplements, get dosage guidance from your healthcare provider. Due to limited research, proper dosages for DIM are unknown. It was the first one that I didn't actually have any leaks. As a result, people looking to treat a specific condition like acne or prostate issues may seek a concentrated dose in the form of a DIM supplement. for every day I don't have a period. Symptoms of estrogen dominance can include: In some instances, estrogen can look normal in labs but the metabolites that are produced in the liver can be problematic. It may also help maintain breast health and could prevent painful breasts (mastalgia). Estrogen imbalances have been linked to weight gain in both men and women, especially during menopause and andropause, when estrogen levels are most variable.